The Howard Johnson Carlisle is located approximately 25 miles from Harrisburg International Airport and two miles from the Appalachian Trail. It's also four miles from the Carlisle Fairgrounds, 30 miles from Gettysburg and the Hershey Chocolate Factory, and 60 miles from Lancaster Amish Country. Hotel amenities include the seasonal outdoor pool, full-service restaurant and cocktail lounge, free parking, ice/vending machines, valet laundry service, and 24-hour front desk service. All rooms have clock radios, hairdryers, and cable TV.

The Howard Johnson Carlisle is located approximately 25 miles from Harrisburg International Airport and two miles from the Appalachian Trail.