On the Cable Car line, the Best Western Tuscan Inn at Fisherman's Wharf is located a block away from Pier 39 and approximately 16 miles from the San Francisco International Airport. The onsite Cafe Pescatore features Italian cuisine. Guests can enjoy complimentary coffee, tea, and biscottis every morning and a complimentary wine reception in the evening. The hotel also offers room service, concierge service, meeting space, 24-hour front desk service, laundry valet, passes to nearby fitness facilities, and valet parking (daily fee) including in-and-out privileges. The hotel has 221 rooms and 12 one-bedroom suites. Non-smoking rooms and rooms equipped for the physically challenged are available. Standard amenities include stocked minibar, refrigerator, coffeemaker, phone dataports, and hairdryer.

Tuscan Inn is a stylish boutique hotel with the decidedly Italian style of a Tuscan countryside lodge.