Located at Taylor and O'Farrell Streets, the Hotel Serrano is situated just three blocks from Union Square and the Theatre District, five blocks from Moscone Convention Center and a ten-minute cab ride to the Financial District. The hotel includes personalized room preferences and welcome amenities for Kimpton InTouch guest loyalty members, valet parking, 24-hour fitness center, laundry service, high-speed internet access, cable TV, 24-hour business center, and a wine reception every evening featuring Kimpton's signature wines of the world. The hotel also features a 14-person steam room and private massage room. All rooms and suites include 19 luxury suites and executive kings (some with oversized jacuzzis and rainfall multi-head showers), iHome stereo with iPod docking station, telephones with dataport and personalized voicemail, wall mounted hair dryer, safes, thick terrycloth bathrobes, irons and ironing boards, room service, and much more. The environmental program, Kimpton Hotels EarthCare, supports a sustainable world by using non-intrusive, high quality, eco-friendly products and services, including In-Room recycling bins, non-toxic cleaners, organic honor bar items and water/energy efficient measures. Kimpton Hotels EarthCare products and practices are based on California Environmental Protection Agency (EPA) Green Lodging Guidelines.

Located at Taylor and O'Farrell Streets, the Hotel Serrano is situated just three blocks from Union Square and the Theatre District, five blocks from Moscone Convention Center and a ten-minute cab ride to the Financial District.