Holiday Inn Express and Suites South Side is located approximately half a mile from Mellon Arena and Station Square and 19 miles from Pittsburgh International Airport. This location is also half a mile from Duquesne University, two miles from Heinz Field and PNC Park, and six miles from the waterfront. The property's amenities include the indoor pool, whirlpool, exercise room, lobby fireplace, and complimentary continental breakfast. The hotel also offers self-service laundry facilities, valet laundry service, a paid parking area, and complimentary high-speed Internet access in the lobby area. The hotel has a restaurant on site, Amalfi, that serves lunch and dinner. Room service is also offered. All rooms feature complimentary high-speed Internet access, cable TV, in-room movies, coffeemakers, irons and ironing boards, and hairdryers.

Holiday Inn Express and Suites South Side is located approximately half a mile from Mellon Arena and Station Square and 19 miles from Pittsburgh International Airport.